News Feed
Is the oxytocin system a keystone in human wellbeing?
It has also taken over a century for science to fully realize that oxytocin is far more than a “female reproductive hormone.” Both the measurement and interpretation of the biochemical and functional properties of…
Asymmetric encoder-decoder U-net with hybrid attention and residual dilated convolution for brain tumor segmentation
InroductionThe accurate and automatic segmentation of brain tumors from magnetic resonance imaging is regarded as essential for clinical diagnosis and surgical planning. Nevertheless, the concurrent extraction of both local fine details and global contextual…
News
3048 results
e-Perinatal Butterfly: An Embedded Study for Parents Experiencing Perinatal Loss
Conditions: Depressive Symptoms; Perinatal Loss; Perinatal Grief; Anxiety Symptoms Interventions: Behavioral: e-Perinatal Butterfly; Other: Standard routine maternal care Sponsors: University of Seville; Andalusian Health Service Not yet recruiting
AI-Based CBT Chatbot for Adolescent Social Anxiety
Conditions: AI-CBT Intervention Group; Waitlist Control Group Interventions: Behavioral: AI-CBT intervention group Sponsors: Central China Normal University Not yet recruiting
STAT+: Roche gets a lung cancer win with its KRAS drug divarasib
One of the more impressive data sets at this year’s ESMO came from a Roche study of its drug divarasib, which treats lung cancer.
Effect of ultrasound-guided stellate ganglion block on intraoperative hemodynamics in laparoscopic partial adrenalectomy: a randomized clinical trial
PurposeThis study aimed to evaluate the effect of ultrasound-guided stellate ganglion block (SGB) on intraoperative hemodynamic parameters in patients undergoing laparoscopic partial adrenalectomy.Patients and methodsA total of 72 patients with adrenal tumors scheduled for laparoscopic partial adrenalectomy were enrolled and…
Evaluating the role of craniocervical and atlantoaxial instability in autonomic dysfunction: a narrative review
BackgroundAutonomic dysfunction is a complex condition that affects every organ system in the body. The underlying mechanisms of autonomic dysfunction remain incompletely understood. There appears to be an association between patients with hypermobile Ehlers Danlos syndrome (hEDS), craniocervical instability (CCI),…
ECG Holter-based screening for sleep-disordered breathing in post-stroke patients: a large monocentric cohort study
IntroductionSleep-disordered breathing (SDB) is highly prevalent after stroke and is associated with poor functional outcomes and increased mortality, yet systematic screening remains challenging because of limited polysomnography accessibility. We evaluated three electrocardiogram (ECG)-based indices for SDB screening in a large…
Hyperhomocysteinemia and Klotho in kidney-to-brain signaling: a metabolic stress-resilience framework for neurovascular dysfunction
Hyperhomocysteinemia (HHcy) and Klotho deficiency are commonly investigated in separate metabolic, renal, vascular, and neurological contexts, yet together they may illuminate how peripheral dysfunction is translated into cerebral vulnerability. This review develops a kidney-to-brain stress resilience framework in which HHcy…
Case Report: Cerebral air embolism following fluid–air exchange during pars plana vitrectomy: a rare but severe complication
Cerebral air embolism (CAE) is a rare but potentially life-threatening neurological emergency, typically caused by the inadvertent entry of exogenous air into the venous circulation and subsequent migration to the cerebral vasculature. It presents with abrupt onset and a prognosis…
Comparative efficacy and safety of quetiapine versus other atypical antipsychotics for behavioral and psychological symptoms in Alzheimer’s disease: a systematic review and meta-analysis
BackgroundThe management of behavioral and psychological symptoms of dementia (BPSD) in Alzheimer’s disease (AD) remains a significant challenge. While atypical antipsychotics are used, their comparative efficacy and safety, particularly for quetiapine, are not well-established within a homogeneous AD population. This…
Multiscale EEG network alterations in adolescents with depressive symptoms: static–dynamic connectivity, topological features, and exploratory scalp-level network hubs
BackgroundAdolescence is a critical period for brain network development and a vulnerable stage for the emergence of depressive symptoms Although altered brain connectivity has been reported in depression, the multiscale organization of resting-state EEG networks in adolescents with depressive symptoms…
Predicting behavioral escalation in students with autism using physiological and movement data
IntroductionBehavioral escalation in students with Autism Spectrum Disorder (ASD) presents significant challenges in educational and community settings, often leading to reactive interventions after behaviors become observable. This study investigated whether physiological and movement data obtained from wearable biometric sensors could…
Substance use among helping professionals: rationalization and negotiation of professional identity
IntroductionGiven the scarce research on the drug use situation among helping professionals and the existing organizational structures that may affect them, this study explores how helping professionals in Hong Kong make sense of personal drug use and negotiate professional identity.MethodsNarrative,…
Transplantation tolerance versus immune evasion: Mechanistic divergences and therapeutic frontiers for islet cell replacement
Deuse et al. review emerging strategies to overcome the toxicities of chronic immunosuppression that limit allogeneic islet transplantation. This review contrasts fragile recipient-centric tolerance induction—vulnerable to destabilization by infections, heterologous immunity, and inflammation—with robust product-centric immune evasion engineered for hypoimmunity,…
Implantable Neuromodulation Devices in Psychiatry: Human Fidelity and Implementation Challenges
American Journal of Psychiatry, Volume 183, Issue 10, Page 743-753, October 01, 2026.
Bilateral Theta-Burst Stimulation of Dorsolateral Prefrontal Cortex Regions for Late-Life Depression: A Randomized, Sham-Controlled Clinical Trial
American Journal of Psychiatry, Volume 183, Issue 10, Page 797-805, October 01, 2026.
Clinical and Cognitive Outcomes Comparing Right Unilateral Ultrabrief Electroconvulsive Therapy Versus Magnetic Seizure Therapy for Bipolar Depression: The CORRECT-BD Trial
American Journal of Psychiatry, Volume 183, Issue 10, Page 754-763, October 01, 2026.
[Comment] Preventing perinatal depression relapse
Mental health conditions are a leading cause of pregnancy-related deaths in the USA, affecting at least 20% of individuals in pregnancy and postpartum.1 Psychiatric relapse and emergencies in the perinatal period are disproportionately greater for women with a history of…
[Comment] Action needed to address HbA1C and weight increases in people initiating antipsychotic medicines
Juan Bazo-Alvarez and colleagues1 present a compelling study investigating trajectories of HbA1C concentration and bodyweight before and after the initiation of second-generation antipsychotic medicines in adults living with severe mental illness (SMI). The findings provide valuable real-world data from electronic…
STAT+: Nonprofit Bon Secours Mercy Health strikes $5.7 billion deal for surgery center chain
The deal would make the Catholic system one of the largest operators of outpatient surgery centers.
News Feed
Is the oxytocin system a keystone in human wellbeing?
It has also taken over a century for science to fully realize that oxytocin is far more than a “female reproductive hormone.” Both the measurement and interpretation of the biochemical and functional properties of…
Asymmetric encoder-decoder U-net with hybrid attention and residual dilated convolution for brain tumor segmentation
InroductionThe accurate and automatic segmentation of brain tumors from magnetic resonance imaging is regarded as essential for clinical diagnosis and surgical planning. Nevertheless, the concurrent extraction of both local fine details and global contextual…
News
3048 results
e-Perinatal Butterfly: An Embedded Study for Parents Experiencing Perinatal Loss
Conditions: Depressive Symptoms; Perinatal Loss; Perinatal Grief; Anxiety Symptoms Interventions: Behavioral: e-Perinatal Butterfly; Other: Standard routine maternal care Sponsors: University of Seville; Andalusian Health Service Not yet recruiting
AI-Based CBT Chatbot for Adolescent Social Anxiety
Conditions: AI-CBT Intervention Group; Waitlist Control Group Interventions: Behavioral: AI-CBT intervention group Sponsors: Central China Normal University Not yet recruiting
STAT+: Roche gets a lung cancer win with its KRAS drug divarasib
One of the more impressive data sets at this year’s ESMO came from a Roche study of its drug divarasib, which treats lung cancer.
Effect of ultrasound-guided stellate ganglion block on intraoperative hemodynamics in laparoscopic partial adrenalectomy: a randomized clinical trial
PurposeThis study aimed to evaluate the effect of ultrasound-guided stellate ganglion block (SGB) on intraoperative hemodynamic parameters in patients undergoing laparoscopic partial adrenalectomy.Patients and methodsA total of 72 patients with adrenal tumors scheduled for laparoscopic partial adrenalectomy were enrolled and…
Evaluating the role of craniocervical and atlantoaxial instability in autonomic dysfunction: a narrative review
BackgroundAutonomic dysfunction is a complex condition that affects every organ system in the body. The underlying mechanisms of autonomic dysfunction remain incompletely understood. There appears to be an association between patients with hypermobile Ehlers Danlos syndrome (hEDS), craniocervical instability (CCI),…
ECG Holter-based screening for sleep-disordered breathing in post-stroke patients: a large monocentric cohort study
IntroductionSleep-disordered breathing (SDB) is highly prevalent after stroke and is associated with poor functional outcomes and increased mortality, yet systematic screening remains challenging because of limited polysomnography accessibility. We evaluated three electrocardiogram (ECG)-based indices for SDB screening in a large…
Hyperhomocysteinemia and Klotho in kidney-to-brain signaling: a metabolic stress-resilience framework for neurovascular dysfunction
Hyperhomocysteinemia (HHcy) and Klotho deficiency are commonly investigated in separate metabolic, renal, vascular, and neurological contexts, yet together they may illuminate how peripheral dysfunction is translated into cerebral vulnerability. This review develops a kidney-to-brain stress resilience framework in which HHcy…
Case Report: Cerebral air embolism following fluid–air exchange during pars plana vitrectomy: a rare but severe complication
Cerebral air embolism (CAE) is a rare but potentially life-threatening neurological emergency, typically caused by the inadvertent entry of exogenous air into the venous circulation and subsequent migration to the cerebral vasculature. It presents with abrupt onset and a prognosis…
Comparative efficacy and safety of quetiapine versus other atypical antipsychotics for behavioral and psychological symptoms in Alzheimer’s disease: a systematic review and meta-analysis
BackgroundThe management of behavioral and psychological symptoms of dementia (BPSD) in Alzheimer’s disease (AD) remains a significant challenge. While atypical antipsychotics are used, their comparative efficacy and safety, particularly for quetiapine, are not well-established within a homogeneous AD population. This…
Multiscale EEG network alterations in adolescents with depressive symptoms: static–dynamic connectivity, topological features, and exploratory scalp-level network hubs
BackgroundAdolescence is a critical period for brain network development and a vulnerable stage for the emergence of depressive symptoms Although altered brain connectivity has been reported in depression, the multiscale organization of resting-state EEG networks in adolescents with depressive symptoms…
Predicting behavioral escalation in students with autism using physiological and movement data
IntroductionBehavioral escalation in students with Autism Spectrum Disorder (ASD) presents significant challenges in educational and community settings, often leading to reactive interventions after behaviors become observable. This study investigated whether physiological and movement data obtained from wearable biometric sensors could…
Substance use among helping professionals: rationalization and negotiation of professional identity
IntroductionGiven the scarce research on the drug use situation among helping professionals and the existing organizational structures that may affect them, this study explores how helping professionals in Hong Kong make sense of personal drug use and negotiate professional identity.MethodsNarrative,…
Transplantation tolerance versus immune evasion: Mechanistic divergences and therapeutic frontiers for islet cell replacement
Deuse et al. review emerging strategies to overcome the toxicities of chronic immunosuppression that limit allogeneic islet transplantation. This review contrasts fragile recipient-centric tolerance induction—vulnerable to destabilization by infections, heterologous immunity, and inflammation—with robust product-centric immune evasion engineered for hypoimmunity,…
Implantable Neuromodulation Devices in Psychiatry: Human Fidelity and Implementation Challenges
American Journal of Psychiatry, Volume 183, Issue 10, Page 743-753, October 01, 2026.
Bilateral Theta-Burst Stimulation of Dorsolateral Prefrontal Cortex Regions for Late-Life Depression: A Randomized, Sham-Controlled Clinical Trial
American Journal of Psychiatry, Volume 183, Issue 10, Page 797-805, October 01, 2026.
Clinical and Cognitive Outcomes Comparing Right Unilateral Ultrabrief Electroconvulsive Therapy Versus Magnetic Seizure Therapy for Bipolar Depression: The CORRECT-BD Trial
American Journal of Psychiatry, Volume 183, Issue 10, Page 754-763, October 01, 2026.
[Comment] Preventing perinatal depression relapse
Mental health conditions are a leading cause of pregnancy-related deaths in the USA, affecting at least 20% of individuals in pregnancy and postpartum.1 Psychiatric relapse and emergencies in the perinatal period are disproportionately greater for women with a history of…
[Comment] Action needed to address HbA1C and weight increases in people initiating antipsychotic medicines
Juan Bazo-Alvarez and colleagues1 present a compelling study investigating trajectories of HbA1C concentration and bodyweight before and after the initiation of second-generation antipsychotic medicines in adults living with severe mental illness (SMI). The findings provide valuable real-world data from electronic…
STAT+: Nonprofit Bon Secours Mercy Health strikes $5.7 billion deal for surgery center chain
The deal would make the Catholic system one of the largest operators of outpatient surgery centers.