News Feed
Discharge Mobility After Osteoporotic Thoracolumbar Fractures Using a 2-Stage Machine Learning Prediction Model: Prospective Cohort Study
Background: Discharge mobility after osteoporotic vertebral fractures is heterogeneous and difficult to predict at admission. Machine learning offers structured approaches for multiclass functional outcome prediction, but existing models predominantly address binary end points and…
Single-Nucleus Multi-Omic Profiling Reveals Muscle Genetic Regulation Layer
Population-scale transcriptomics and chromatin accessibility profiling uncover thousands of disease-associated regulatory signals missed by transcriptomic analyses, raising questions about how many therapeutic targets are unknown. The post Single-Nucleus Multi-Omic Profiling Reveals Muscle Genetic Regulation…
Short-Term Low-Fat Diet Has Lasting Inflammatory Disease Benefits
Switching low-fat diet for just a few days at the onset of an inflammatory disease such as psoriasis could impact its trajectory in both the short and long term, according to a preclinical study.…
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3069 results
Birmingham trusts launch InterSystems shared patient portal
Birmingham and Solihull Mental Health and Birmingham Community Healthcare NHS Foundation Trusts have launched a shared patient portal.
Evaluating Wearable Devices for Remote Monitoring in Psychosis: Pilot Study Nested Within the CONNECT Cohort Study
Background: Digital remote monitoring technologies, including smartphones and wearables, offer promising avenues for early detection of psychosis relapse. However, selecting devices that are acceptable to participants and produce high-quality data remains challenging. Objective: The aim of this nested pilot study…
Loneliness From the Digital Mental Health Practitioners’ Perspective: Thematic Analysis of Semistructured Interviews
Background: Loneliness is a prevalent concern across the United Kingdom. While validated scales exist to quantify the severity of loneliness across populations, there remains a gap in understanding how loneliness manifests and is addressed within therapeutic practice. Given the associated…
AI Reveals Hidden Brain Lesions in Multiple Sclerosis MRI
Researchers combined AI with multiple image processing methods to reliably measure on existing multiple sclerosis MRI scans cortical lesions strongly implicated in disability and cognitive, which would previously have remained undetected. The post AI Reveals Hidden Brain Lesions in Multiple…
STAT+: FDA approves Vera Therapeutics kidney disease treatment
The FDA approved a new medicine from the biotech company Vera Therapeutics for patients with a type of chronic autoimmune kidney disease.
STAT+: The crumbling employer-based health insurance system
Today's D.C. Diagnosis newsletter covers maintaining diversity in drug trials and troubling trends in employer-based health insurance.
STAT+: Compass says depression drug has long-lasting benefits
Vertex makes its largest-ever deal, skyrocketing health insurance costs, and more biotech news from The Readout
STAT+: America’s employer health insurance is decaying
STAT's Bob Herman examines the under-the-radar crisis brewing in employer-based health insurance.
STAT+: ‘Secret shopper’ study probes GLP-1 telehealth sites
In this edition of STAT Health Tech: A 'secret shopper' study of telehealth sites prescribing GLP-1s, news about Epic, Anthropic, and brain implants.
The Download: your stake in OpenAI, and the Treasury’s AI warning
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Your family’s $300 stake in OpenAI Sam Altman’s proposal that Americans should share in the wealth…
Prototypical graph based deep label propagation with semantic augmentation for cross-subject and cross-session EEG emotion recognition
Electroencephalogram (EEG)-based emotion recognition faces significant generalization challenges in cross-subject and cross-session settings, primarily due to the inherent non-stationarity, individual differences, and semantic deficiency of EEG signals. To address these challenges and enhance the universality of affective brain-computer interface systems,…
Lower limb rehabilitation in chronic incomplete SCI: a randomized controlled trial protocol comparing combined TMS-tSCS neuromodulation vs. tSCS alone
BackgroundSpinal cord injury (SCI) affects 15.4 million people worldwide, with a substantial proportion of incomplete SCI patients remaining non-ambulatory, highlighting the importance of motor function recovery and mobility in rehabilitation. While transcutaneous spinal cord stimulation (tSCS) has emerged as a…
Development of a transformation model to analyze horizontal saccadic velocity using electrooculography: a pilot feasibility study
IntroductionSaccadic eye movements are established biomarkers in neuroscience and clinical neurology, with video-oculography (VOG) serving as the gold standard for measurement. However, the high cost, bulky equipment, and poor portability of VOG systems restrict their clinical utility. Electrooculography (EOG) provides…
A dual-branch network with brain region-constrained attention for EEG emotion recognition
IntroductionElectroencephalography (EEG)-based emotion recognition provides an objective avenue for affective computing. However, the complexity of EEG signals across temporal, frequency, and spatial domains makes any single dimension inadequate.MethodsTo overcome these limitations, we propose the Brain Region-Constrained Attention Dual-Branch Network (BRAD-Net).…
Comparative meta-analysis of task-related functional brain abnormalities in nonsuicidal self-injury and suicide attempt
BackgroundNonsuicidal self-injury (NSSI) and suicide attempt (SA) are two major self-injurious behaviors causing substantial suffering and socioeconomic burden. However, it remains unclear whether NSSI and SA are characterized by common or distinct brain dysregulations. Here, we aimed to identify shared…
The reliability and diagnostic accuracy of the GAD-7 and GAD-2 for the most prevalent anxiety disorders in Latvian primary care
IntroductionAnxiety disorders are common but often under-recognized in primary care. Validation data for the GAD-7 and GAD-2 in Eastern European primary care settings remain limited. To determine the reliability and diagnostic performance of the GAD-7 and GAD-2 for the most…
Research progress on addictive features and reward circuit mechanisms in non-suicidal self-injury and the feasibility of precision neuromodulation
Non-Suicidal Self-Injury (NSSI) presents a significant public health challenge; however, its underlying neurobiological mechanisms remain insufficiently understood, limiting the development of targeted interventions. Emerging evidence suggests that NSSI exhibits core addictive features, such as compulsive urges and tolerance, which may…
Self-esteem and inner strengths: a network study in Thai university students with borderline personality disorder symptoms
IntroductionSelf-esteem is widely regarded as an important construct in the psychological functioning of individuals with borderline personality disorder (BPD) symptoms. During emerging adulthood, fluctuations in self-esteem are often linked to emotional dysregulation and maladaptive adjustment; however, self-esteem has rarely been…
Hair cortisol as psychotherapy process parameter – an inpatient pediatric psychosomatic study
IntroductionPediatric-psychosomatic inpatient therapy is an essential part of the German health care system for the treatment of mental disorders in children and adolescents. However, empirical research in this field remains scarce and limited to psychological parameters. This longitudinal naturalistic study…
News Feed
Discharge Mobility After Osteoporotic Thoracolumbar Fractures Using a 2-Stage Machine Learning Prediction Model: Prospective Cohort Study
Background: Discharge mobility after osteoporotic vertebral fractures is heterogeneous and difficult to predict at admission. Machine learning offers structured approaches for multiclass functional outcome prediction, but existing models predominantly address binary end points and…
Single-Nucleus Multi-Omic Profiling Reveals Muscle Genetic Regulation Layer
Population-scale transcriptomics and chromatin accessibility profiling uncover thousands of disease-associated regulatory signals missed by transcriptomic analyses, raising questions about how many therapeutic targets are unknown. The post Single-Nucleus Multi-Omic Profiling Reveals Muscle Genetic Regulation…
Short-Term Low-Fat Diet Has Lasting Inflammatory Disease Benefits
Switching low-fat diet for just a few days at the onset of an inflammatory disease such as psoriasis could impact its trajectory in both the short and long term, according to a preclinical study.…
News
3069 results
Birmingham trusts launch InterSystems shared patient portal
Birmingham and Solihull Mental Health and Birmingham Community Healthcare NHS Foundation Trusts have launched a shared patient portal.
Evaluating Wearable Devices for Remote Monitoring in Psychosis: Pilot Study Nested Within the CONNECT Cohort Study
Background: Digital remote monitoring technologies, including smartphones and wearables, offer promising avenues for early detection of psychosis relapse. However, selecting devices that are acceptable to participants and produce high-quality data remains challenging. Objective: The aim of this nested pilot study…
Loneliness From the Digital Mental Health Practitioners’ Perspective: Thematic Analysis of Semistructured Interviews
Background: Loneliness is a prevalent concern across the United Kingdom. While validated scales exist to quantify the severity of loneliness across populations, there remains a gap in understanding how loneliness manifests and is addressed within therapeutic practice. Given the associated…
AI Reveals Hidden Brain Lesions in Multiple Sclerosis MRI
Researchers combined AI with multiple image processing methods to reliably measure on existing multiple sclerosis MRI scans cortical lesions strongly implicated in disability and cognitive, which would previously have remained undetected. The post AI Reveals Hidden Brain Lesions in Multiple…
STAT+: FDA approves Vera Therapeutics kidney disease treatment
The FDA approved a new medicine from the biotech company Vera Therapeutics for patients with a type of chronic autoimmune kidney disease.
STAT+: The crumbling employer-based health insurance system
Today's D.C. Diagnosis newsletter covers maintaining diversity in drug trials and troubling trends in employer-based health insurance.
STAT+: Compass says depression drug has long-lasting benefits
Vertex makes its largest-ever deal, skyrocketing health insurance costs, and more biotech news from The Readout
STAT+: America’s employer health insurance is decaying
STAT's Bob Herman examines the under-the-radar crisis brewing in employer-based health insurance.
STAT+: ‘Secret shopper’ study probes GLP-1 telehealth sites
In this edition of STAT Health Tech: A 'secret shopper' study of telehealth sites prescribing GLP-1s, news about Epic, Anthropic, and brain implants.
The Download: your stake in OpenAI, and the Treasury’s AI warning
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Your family’s $300 stake in OpenAI Sam Altman’s proposal that Americans should share in the wealth…
Prototypical graph based deep label propagation with semantic augmentation for cross-subject and cross-session EEG emotion recognition
Electroencephalogram (EEG)-based emotion recognition faces significant generalization challenges in cross-subject and cross-session settings, primarily due to the inherent non-stationarity, individual differences, and semantic deficiency of EEG signals. To address these challenges and enhance the universality of affective brain-computer interface systems,…
Lower limb rehabilitation in chronic incomplete SCI: a randomized controlled trial protocol comparing combined TMS-tSCS neuromodulation vs. tSCS alone
BackgroundSpinal cord injury (SCI) affects 15.4 million people worldwide, with a substantial proportion of incomplete SCI patients remaining non-ambulatory, highlighting the importance of motor function recovery and mobility in rehabilitation. While transcutaneous spinal cord stimulation (tSCS) has emerged as a…
Development of a transformation model to analyze horizontal saccadic velocity using electrooculography: a pilot feasibility study
IntroductionSaccadic eye movements are established biomarkers in neuroscience and clinical neurology, with video-oculography (VOG) serving as the gold standard for measurement. However, the high cost, bulky equipment, and poor portability of VOG systems restrict their clinical utility. Electrooculography (EOG) provides…
A dual-branch network with brain region-constrained attention for EEG emotion recognition
IntroductionElectroencephalography (EEG)-based emotion recognition provides an objective avenue for affective computing. However, the complexity of EEG signals across temporal, frequency, and spatial domains makes any single dimension inadequate.MethodsTo overcome these limitations, we propose the Brain Region-Constrained Attention Dual-Branch Network (BRAD-Net).…
Comparative meta-analysis of task-related functional brain abnormalities in nonsuicidal self-injury and suicide attempt
BackgroundNonsuicidal self-injury (NSSI) and suicide attempt (SA) are two major self-injurious behaviors causing substantial suffering and socioeconomic burden. However, it remains unclear whether NSSI and SA are characterized by common or distinct brain dysregulations. Here, we aimed to identify shared…
The reliability and diagnostic accuracy of the GAD-7 and GAD-2 for the most prevalent anxiety disorders in Latvian primary care
IntroductionAnxiety disorders are common but often under-recognized in primary care. Validation data for the GAD-7 and GAD-2 in Eastern European primary care settings remain limited. To determine the reliability and diagnostic performance of the GAD-7 and GAD-2 for the most…
Research progress on addictive features and reward circuit mechanisms in non-suicidal self-injury and the feasibility of precision neuromodulation
Non-Suicidal Self-Injury (NSSI) presents a significant public health challenge; however, its underlying neurobiological mechanisms remain insufficiently understood, limiting the development of targeted interventions. Emerging evidence suggests that NSSI exhibits core addictive features, such as compulsive urges and tolerance, which may…
Self-esteem and inner strengths: a network study in Thai university students with borderline personality disorder symptoms
IntroductionSelf-esteem is widely regarded as an important construct in the psychological functioning of individuals with borderline personality disorder (BPD) symptoms. During emerging adulthood, fluctuations in self-esteem are often linked to emotional dysregulation and maladaptive adjustment; however, self-esteem has rarely been…
Hair cortisol as psychotherapy process parameter – an inpatient pediatric psychosomatic study
IntroductionPediatric-psychosomatic inpatient therapy is an essential part of the German health care system for the treatment of mental disorders in children and adolescents. However, empirical research in this field remains scarce and limited to psychological parameters. This longitudinal naturalistic study…