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Evaluating the Impact of Ketogenic Therapy on Symptom Severity and Metabolic Side Effect Profile Among Individuals Living With Bipolar Disorder in A Rural Southern Catchment Area
Conditions: Bipolar Disorder Interventions: Dietary Supplement: Ketogenic foodstuffs; Other: Standard of Care Oral antipsychotics; Other: Standard of care long acting injectable medication for bipolar disorder Sponsors: University of Alabama at Birmingham; Baszucki Family Foundation; Baptist Health System Montgomery Not yet…
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
Conditions: Borderline Personality Disorder (BPD); Treatment-Resistant Major Depressive Disorder; Treatment-resistant Bipolar Depression; Major Depressive Disorder (MDD); Bipolar Disorder (BD); Bipolar Disorder I or II; Suicidal Ideation Interventions: Drug: Ketamine Hydrochloride; Drug: Midazolam Hydrochloride; Behavioral: Dialectical Behavioral Therapy (DBT) Sponsors: Joshua…
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
Conditions: PTSD - Post Traumatic Stress Disorder; PTSD; PTSD Symptoms; PTSD, Post Traumatic Stress Disorder Interventions: Drug: COMP360 psilocybin Sponsors: COMPASS Pathways Not yet recruiting
A PIVOT towards single-cell functional genetic screening in plants
Nature Biotechnology, Published online: 05 May 2026; doi:10.1038/s41587-026-03141-0We developed PIVOT, a single-cell screening platform for functional characterization of plant genes. PIVOT enables delivery of gene libraries to tobacco leaves with single multiplicity of infection and magnetic sorting of single plant…
Autonomous pathology research using agentic AI shows potential in oncology
Nature Medicine, Published online: 05 May 2026; doi:10.1038/s41591-026-04403-9The agentic artificial intelligence tool SPARK is able to reproduce pathology-based reasoning and produce biological hypotheses and relevant diagnostic, prognostic and predictive cellular parameters. The output of SPARK has the potential to advance…
Author Correction: Benralizumab versus placebo for hypereosinophilic syndrome: a randomized, placebo-controlled phase 3 trial
Nature Medicine, Published online: 05 May 2026; doi:10.1038/s41591-026-04425-3Author Correction: Benralizumab versus placebo for hypereosinophilic syndrome: a randomized, placebo-controlled phase 3 trial
Personalized fMRI-Guided TMS Targeting the Threat Neurocircuitry in PTSD: A Randomized Clinical Trial
American Journal of Psychiatry, Volume 183, Issue 5, Page 343-354, May 01, 2026.
Resting-State Functional Connectivity of the Amygdala and Hippocampus in PTSD: Results From the PGC-ENIGMA PTSD Working Group
American Journal of Psychiatry, Volume 183, Issue 5, Page 333-342, May 01, 2026.
The Future of DSM: Role of Candidate Biomarkers and Biological Factors
American Journal of Psychiatry, Volume 183, Issue 5, Page 317-324, May 01, 2026.
The Future of DSM: A Report From the Structure and Dimensions Subcommittee
American Journal of Psychiatry, Volume 183, Issue 5, Page 301-309, May 01, 2026.
Psychiatric Comorbidities in Substance Use Disorders: Sex-Based Differences in a National Real-World Clinical Sample
American Journal of Psychiatry, Volume 183, Issue 5, Page 355-363, May 01, 2026.
Anxiety and Depression Associated With the Dependent Use of Generative AI in Medical Students: Cross-Sectional Study
Background: The growing integration of artificial intelligence (AI) in higher education has transformed learning processes but also raised concerns about potential mental health risks. Medical students represent a particularly vulnerable group due to high academic stress and increasing reliance on…
STAT+: Did AI really beat doctors at diagnosis?
In this edition of STAT Health Tech: A high-profile study on AI's diagnostic capabilities, role of telehealth in abortion access, and an Epic lawsuit.
Psilocybin-Induced Brain Changes May Explain Therapeutic Effects
The results of a study carried out in human volunteers given a single dose of psilocybin link changes in brain entropy to insight and suggest that the psychedelic trip itself is important to the drug’s longer term therapeutic effects. The…
Statement on Mental Health and Access to Evidence-Based Care
The IOCDF is proud to be a member of the Mental Health Liaison Group, which distributed the below statement. To learn more about appropriate treatment for OCD, including the use... Read more » The post Statement on Mental Health and…
Genotype-Guided Antidepressants Could Have Long-Term Benefits
Prescribing selective serotonin reuptake inhibitors according to a patient’s genetic makeup may have benefits, but these may only become apparent in the long term. The post Genotype-Guided Antidepressants Could Have Long-Term Benefits appeared first on Inside Precision Medicine.
STAT+: Pharma’s reputation among patient groups rose last year, but concerns remain over access and pricing
The pharma industry saw its reputation among patient groups inch up last year, a new survey finds, but concerns remain over access and pricing.
STAT+: A new attack on AMA’s billing codes
A key GOP lawmaker is broadening the party's efforts to combat health care fraud.
STAT+: Are analysts too quick to gloss over Lilly’s liver case?
Cytokinetics' Myqorzo's trial results, Johnson & Johnson's IBD therapy, and more biotech news from The Readout
STAT+: Pharmalittle: We’re reading about RFK Jr. targeting antidepressants, J&J pushing an IBD drug, and more
HHS Secretary Robert F. Kennedy Jr. announced initiatives to rein in prescribing of SSRIs, the most widely used antidepressants

