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The PREVENT Resilience Study
Conditions: Psychological Trauma Interventions: Device: Transcranial Magnetic Stimulation (TMS); Other: TMS Sham Sponsors: Emory University; National Institute of Mental Health (NIMH) Not yet recruiting
TUBSIS 2.0 – Tobacco Use Behavioral Support and Intervention System
Conditions: Tobacco Use Disorder; Nicotine Dependence; Vaping; Smoking Tobacco Interventions: Behavioral: TUBSIS 2.0 Sponsors: University of Zurich; State Secretariat for Education Research and Innovation, Switzerland Recruiting
Neural Correlates of Suicidal Behavior in Youth
Conditions: Suicidal Ideation; Suicide Attempt; Suicidal Behavior; Depression / Major Depressive Disorder; Hopelessness; Neurobiological Interventions: Behavioral: CAMS Sponsors: The Cleveland Clinic; MQ Mental Health Research Not yet recruiting
Structural Brain Network Alterations in Relation to Treatment and Illness Severity in Bipolar Disorder
Large-scale T1-weighted MRI studies have established grey-matter abnormalities in bipolar disorder (BD), with our group contributing to consensus findings. However, structural connectivity, particularly within emotion- and reward-related circuits, remains poorly understood. Diffusion-weighted MRI (dMRI) enables investigation of white-matter pathways, yet…
Addressing the Psychological Needs of Adolescents During the Wait Time for Mental Health Treatment: Service Design Study
Background: Adolescents waiting for mental health treatment often experience significant unmet psychological needs, including severe psychological distress, increased use of maladaptive coping strategies, and feelings of abandonment. However, current wait time support offerings across the mental health sector are sparse…
Older Adults’ Experiences Navigating Setup of Digital Health Technology: Implementation Report
Background: Digital health and connected technologies may support better health outcomes among older adults, including those with multiple chronic conditions or low engagement in health behaviors. However, initial experiences with technology, including during unboxing, setup, and first use, can influence…
Curiosity in a Novel Virtual Reality Scenario and Its Association With Symptoms of Depression: Observational Pilot Investigation
Background: Curiosity plays a fundamental role in human learning, development, and motivation, and emerging evidence suggests that reduced curiosity is linked to poorer mental health outcomes, including depressive symptoms (DS). However, to date, the majority of curiosity research relies on…
STAT+: French regulator fines Novo and Lilly over weight loss ad campaigns
France's medicines regulator has fined Novo Nordisk and Eli Lilly over their weight loss ad campaigns.
Opinion: Mifepristone court ruling makes drug development riskier for everyone
The 5th Circuit’s ruling on mifepristone “is bad for health care access, and it’s also bad for innovation,” writes Grace E. Colón.
Biomarker of Epigenetic Aging Could Signal Depression
A biomarker of epigenetic aging of white blood cells called monocytes is linked to depression in a study of women with HIV. The post Biomarker of Epigenetic Aging Could Signal Depression appeared first on Inside Precision Medicine.
Week one of the Musk v. Altman trial: What it was like in the room
This story originally appeared in The Algorithm, our weekly newsletter on AI. To get stories like this in your inbox first, sign up here. Two of the most powerful people in AI—Sam Altman and Elon Musk—began their face-off in court in…
Supreme Court restores access to abortion pill mifepristone through telehealth, mail, and pharmacies
The Supreme Court on Monday restored broad access to the abortion pill mifepristone, blocking a ruling that had threatened to upend one of the main ways abortion is provided across the…
Researchers urge study of paternal deaths, though a new paper finds fatherhood is protective
A research letter published on Monday in JAMA Pediatrics argues that paternal mortality deserve more attention
STAT+: Pump the brakes on AI, buddy; and deposition deadlock
It's tough to write nuanced headlines, but a new study on AI in emergency rooms is getting way overhyped.
The Child Mind Institute Names Dr. Vera Feuer as Chief Clinical Officer
Feuer brings more than two decades of clinical leadership to inaugural role New York, NY – The Child Mind Institute, an independent nonprofit dedicated to transforming the lives of children affected by mental health disorders, today announced Vera Feuer, MD, as the organization’s first-ever Chief Clinical Officer. A seasoned specialist in pediatric and adolescent mental health, Dr.…
Tailoring AI solutions for health care needs
The AI market is full of big promises of grand transformation. Health care is a prime target for those promises, beset as it is by financial pressures, labor shortages, and the growing burden of caring for an aging population. AI…
Altered glymphatic function in nasopharyngeal carcinoma following radiotherapy: novel insights from choroid plexus volume and free-water fraction analyses
Background and purposeRadiotherapy (RT) often causes delayed radiation-induced brain injury (RBI) with unclear pathophysiology; emerging evidence links this to glymphatic dysfunction, but radiation effects on cerebrospinal fluid (CSF) dynamics and interstitial fluid-CSF exchange are unstudied. Thus, we used choroid plexus…
Manual therapy ameliorates neuromuscular dysfunction in spastic model rat: involvement of the C-Fiber-mediated CaMKII pathway
BackgroundThis study investigated whether manual therapy applied to tendon organs ameliorated neuromuscular dysfunction in rats with spasticity induced by upper motor neuron injury associated with spastic cerebral palsy, and analyzed the potential involvement of the C-fiber-mediated CaMKII signaling pathway.MethodsMale rats…
Analysis of risk factors for tic disorders in children in Hubei region based on liquid chromatography-tandem mass spectrometry
ObjectiveThis study aims to investigate the correlation between trace element concentrations, 25-hydroxyvitamin D [25(OH)D] levels, and the severity of tic disorders (TD) in children from the Hubei region. Additionally, it seeks to explore the interrelationships among these monitored indicators to…
Sex as a biological variable in amblyopia: implications for developmental plasticity and treatment
Amblyopia is a common childhood visual disorder caused by abnormal visual experience that drives visual cortical plasticity during the sensitive period. The timing and forms of treatment with patching therapy and other therapeutic interventions have been extensively studied; however, sex…