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Long-Read DNA Test Could Replace 15 Existing Tests for Rare Diseases
A DNA test for rare diseases using long-read sequencing can provide much more comprehensive results than standard diagnostics in a shorter amount of time. The post Long-Read DNA Test Could Replace 15 Existing Tests…
Opinion: ‘I’m pretty much all in’: An interview with a woman starting medical residency at almost 73
"There are some physicians that work to 100”: Dawn Zuidgeest-Craft on becoming a medical doctor in her 70s.
Maternal Blood Test Allows Comprehensive Genetic Fetal Screening
Non-invasive fetal sequencing (NIFS), a test developed by scientists at Harvard University, allows comprehensive genetic screening of a fetus using only a blood test from the expectant mother. The post Maternal Blood Test Allows…
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HSV-1 strain H129 co-opts neuronal synaptic transmission machinery for its transsynaptic spread
Nature Neuroscience, Published online: 14 April 2026; doi:10.1038/s41593-026-02254-8By assembling into ‘virion vesicles’, the H129 strain of herpes simplex virus-1 hijacks synaptic machinery for its anterograde spread, co-opting voltage-gated Ca2+ channels, Syt7 and SNAREs for presynaptic exit, then nectin-1/CME for postsynaptic…
A fluoride shortage for some U.S. water systems
An experimental Medicare program, how family dynamics affect brain recovery, and other health news from Morning Rounds
Coming soon: 10 Things That Matter in AI Right Now
Each year we compile our 10 Breakthrough Technologies list, featuring our educated predictions for which technologies will have the biggest impact on how we live and work. This year, however, we had a dilemma. While our final picks encompass all…
The problem with thinking you’re part Neanderthal
You’ve probably heard some version of this idea before: that many of us have an “inner Neanderthal.” That is to say, around 45,000 years ago, when Homo sapiens first arrived in Europe, they met members of a cousin species—the broad-browed,…
Opinion: My brother can’t access a just-approved breakthrough drug for his rare disease
Rare disease clinical trials, policy discussions, and advocacy initiatives often leave adults behind.
STAT+: Dana-Farber CEO talks untangling from Mass General Brigham and building new cancer hospital
Dana-Farber CEO Benjamin Ebert has no shortage of ideas and vision for the cancer institute as it untangles from Mass General Brigham and builds a new hospital.
A top WHO official confronts Iran war fallout, and weighs bid for an even bigger role
The director of WHO's Eastern Mediterranean region is weighing whether to run to be the next director-general at a time of tumult over Iran and beyond.
For Ben Sasse, Revolution Medicines’ pancreatic cancer trial felt like his best, only option
Former Sen. Ben Sasse gives a glimpse of what it's like to be a participant in an tough but promising new drug for pancreatic cancer.
Kent and Medway mental health appointments launch online
Kent and Medway Mental Health NHS Trust has a launched a portal to give patients 24/7 online access to their mental health appointments.
Symptoms of Anxiety and/or Depression and SDM in Older Patients With CLTI
Conditions: Critical Limb Threatening Ischaemia; Depression Disorder; Anxiety Sponsors: Guy's and St Thomas' NHS Foundation Trust; University Hospitals, Leicester Not yet recruiting
Efficacy and Safety of a Theta Burst Stimulation Protocol of Repetitive Transcranial Magnetic Stimulation in Treatment-Resistant Depression
Conditions: Major Depressive Disorder (MDD); Depression - Major Depressive Disorder Interventions: Drug: antidepressant therapy; Device: Active rTMS Theta Burst Stimulation; Device: Sham Stimulation Sponsors: Jung-Sun Lee; Korea Health Industry Development Institute; Seoul National University Hospital; Nowon Eulji Medical Center, Eulji…
Early Brainwave Biomarkers for Personalized Neuromodulation in Treatment-resistant Depression
Conditions: Major Depressive Disorder; Treatment Resistant Depression Interventions: Device: Personalized iTBS; Device: Non-Personalized iTBS; Device: Sham iTBS Sponsors: Stanford University; National Institute of Mental Health (NIMH) Not yet recruiting
Effectiveness of Behavioral Activation Group Therapy for Patients With Depression at the Community in Thanh Hoa
Conditions: Depression - Major Depressive Disorder Interventions: Behavioral: Behaviral activation group therapy Sponsors: Hanoi Medical University Completed
NIH-funded breakthrough shrinks CRISPR for precision delivery in the body
Smaller gene-editing system could expand treatment options for cancer, ALS and other diseases.
Author Correction: Real-time surveillance system for patient deterioration: a pragmatic cluster-randomized controlled trial
Nature Medicine, Published online: 13 April 2026; doi:10.1038/s41591-026-04382-xAuthor Correction: Real-time surveillance system for patient deterioration: a pragmatic cluster-randomized controlled trial
STAT+: FDA pushes drugmakers to report missing clinical trial results
FDA officials said an internal analysis found results were not submitted for nearly 30% of studies “highly likely” to fall under mandatory reporting requirements.
STAT+: Federal judge tosses California No Surprises Act lawsuit against HaloMD
HaloMD is a middleman that became the top filer of out-of-network billing disputes on behalf of medical providers.
STAT+: Access granted: CMS greenlights more than 150 participants for chronic care experiment
CMS greenlights more than 150 digital health companies for its ACCESS experiment, a new program for tech-backed chronic care with outcome-aligned payments.
Designing Psychologically Grounded Artificial Intelligence for Supporting Bystander-Based Cyberaggression Intervention: Mixed Methods Exploratory Study
Background: Cyberaggression poses a growing threat to mental health, contributing to increased distress, reduced self-esteem, and other adverse psychosocial outcomes. Although bystander intervention can mitigate the escalation and impact of cyberaggression, individuals often lack the confidence, strategies, or language to…
STAT+: Trump goes soft on insurance, and a medical underwriting chart
President Trump vowed to take on health insurers, but his policies tell a different story.