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Expression of Concern for: Nicotine breaks down preformed Alzheimer’s β-amyloid fibrils in vitro
Expression of Concern for: “Nicotine breaks down preformed Alzheimer’s β-amyloid fibrils in vitro,” by Ono et al. (Biol Psychiatry 2002; 52:880–886); https://doi.org/10.1016/S0006-3223(02)01417-8.
Opinion: The podcast bringing together MAHA and public health for hard conversations
“These sides aren't talking to each other. And there's a lot riding on it”: The hosts of “Why Should I Trust You?” on bringing together MAHA and public health.
Optimism for Trump’s CDC pick is tempered by questions about RFK Jr.’s role
As one CDC employee, who asked not to be named, put it on Friday, among staff “the general vibe is guarded but hopeful.”
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STAT+: New Bain biotech startup, building on BMS drugs, gets a name and a CEO
Beeline Medicine is focused on development of five inflammatory and immune disorder drugs, starting with a potential daily pill for lupus.
No one’s sure if synthetic mirror life will kill us all
For four days in February 2019, some 30 synthetic biologists and ethicists hunkered down at a conference center in Northern Virginia to brainstorm high-risk, cutting-edge, irresistibly exciting ideas that the National Science Foundation should fund. By the end of the…
STAT+: Flawed study on the antidepressant Paxil came with a cautionary note — if you knew how to find it
When scientific journals publish expressions of concerns, they have an obligation to do so prominently, Ed Silverman writes.
Opinion: Hosting the ‘intellectual wrestling match’ between MAHA, public health
“These sides aren't talking to each other. And there's a lot riding on it”: the podcast trying to bridge MAHA and public health.
STAT+: AI could check millions of CT scans for heart risk. Who will pay for it?
New AI tools could screen existing CT scans to asses risk for heart disease. But, who'll pay for it, and will it improve health outcomes?
Building trust in the AI era with privacy-led UX
The practice of privacy-led user experience (UX) is a design philosophy that treats transparency around data collection and usage as an integral part of the customer relationship. An undertapped opportunity in digital marketing, privacy-led UX treats user consent not as…
Five Digits Test – Validation of a Neuropsychological Test of Inhibition for Patients With Neuropsychiatric Conditions
Conditions: Autism; ADHD Interventions: Diagnostic Test: Five Digits Test Sponsors: Umeå University; Region Västerbotten Recruiting
Analysis of Influencing Factors for the Development of PTSD in Emergency Department Trauma Patients
Conditions: Trauma Patients; PTSD Sponsors: The First Affiliated Hospital of Air Force Medicial University Not yet recruiting
NASA is building the first nuclear reactor-powered interplanetary spacecraft. How will it work?
MIT Technology Review Explains: Let our writers untangle the complex, messy world of technology to help you understand what’s coming next. You can read more from the series here. Just before Artemis II began its historic slingshot around the moon, Jared…
User Experience and Early Clinical Outcomes of a Mental Wellness Chatbot for Depression and Anxiety: Pilot Evaluation Mixed Methods Study
Background: Artificial intelligence–powered conversational agents (ie, chatbots) are increasingly popular outlets for users seeking psychological support, yet little is known about how users experience early-stage prototypes or which therapeutic processes contribute to clinical improvement. A transparent evaluation of emerging chatbot…
Development of Virtual Mental Health Stepped Care Service for a Heart Failure Remote Management Program: Qualitative Descriptive Study
Background: Depression is highly prevalent yet undertreated among people living with heart failure, indicating barriers to mental health services. Although various digital mental health interventions have been developed to detect, treat, and manage depression in this population, these interventions have…
Redefining the future of software engineering
Software engineering has experienced two seismic shifts this century. First was the rise of the open source movement, which gradually made code accessible to developers and engineers everywhere. Second, the adoption of development operations (DevOps) and agile methodologies took software…
Prediction of Relapse Using Digital Technology in People in Recovery From Substance Use Disorders: Early Economic Evaluation With a Case Study of the Subreal App
Background: Many people relapse after achieving abstinence in substance use disorders. Health care providers may scan the horizon for new technologies to predict response that allow interventions to be targeted rather than routine. Currently, no such predictive technologies are available…
STAT+: Congress returns to a packed health care agenda
The key health care issues we're watching as Congress returns from recess.
STAT+: FDA pressures drugmakers to report trial results
Ben Sasse on enrolling in Rev Med's drug trial, more ADC investment, and other biotech news from The Readout
STAT+: Hospitals offer chatbots to fight off ChatGPT
In this edition of STAT Health Tech: Hospitals offer their own chatbots, Medicare's ACCESS pilot, and an update Utah's 'AI doctor' experiment.
STAT+: Pharmalittle: We’re reading about an FDA push for trial transparency, a Novo-OpenAI deal, and more
The FDA told more than 2,200 companies and researchers that they are required to report clinical trial results, or they may face fines
The Download: the state of AI, and protecting bears with drones
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Want to understand the current state of AI? Check out these charts. If you’re following AI news, you’re probably getting whiplash.…
Mitochondrial dysfunction, neuroinflammation, and associated mechanisms in sepsis-associated encephalopathy: from pathogenesis to emerging therapeutics
Sepsis-associated encephalopathy (SAE) is a devastating neurological complication of sepsis, leading to diffuse brain dysfunction, long-term cognitive deficits, and increased mortality. Its pathogenesis is complex, with mitochondrial dysfunction and neuroinflammation emerging as central, interconnected drivers. This review systematically elucidates the…