News Feed
Is the oxytocin system a keystone in human wellbeing?
It has also taken over a century for science to fully realize that oxytocin is far more than a “female reproductive hormone.” Both the measurement and interpretation of the biochemical and functional properties of…
Asymmetric encoder-decoder U-net with hybrid attention and residual dilated convolution for brain tumor segmentation
InroductionThe accurate and automatic segmentation of brain tumors from magnetic resonance imaging is regarded as essential for clinical diagnosis and surgical planning. Nevertheless, the concurrent extraction of both local fine details and global contextual…
News
3048 results
STAT+: HHS relaxes security, transparency rules for health record software used by hospitals
The Trump administration removed several security, privacy and transparency requirements for vendors of EHR software.
Will the real Anthropic please stand up
This story originally appeared in The Algorithm, our weekly newsletter on AI. To get stories like this in your inbox first, sign up here. After weeks of frenzied speculation, Anthropic has filed its IPO prospectus. The 335-page document (100 pages or…
STAT+: House lawmaker probes PBMs for ‘punitive’ audits of independent pharmacies
A House lawmaker is investigating whether the three largest PMS targeted independent pharmacies withretaliatory audits.
STAT+: GSK sees its return to cancer start to pay off
A decade ago, GSK was out of oncology. It could soon pick up approval for its sixth cancer drug.
STAT+: Merck ADC drug cut risk of death by one-third in advanced endometrial cancer
A Phase 3 trial of a targeted drug developed by Merck and China’s Kelun-Biotech cut by one-third the risk of death in patients with advanced endometrial cancer.
The Download: everyday AI harms and the race to nuclear spaceflight
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Opinion: The focus on AI safety disasters ignores everyday harms —Sam Hiner, cofounder of the Young…
The focus on AI safety disasters ignores everyday harms
Consider what passes for success in technology policy. An AI company promises that its chatbot will not encourage suicide. A social media platform makes it more difficult for children to buy fentanyl. These are important protections, and they should have…
Assessment of the Seasonality of Depressive Symptoms in Adolescents
Conditions: Depressive Symptoms Interventions: Diagnostic Test: Measuring the intensity of the seasonality of depressive symptoms in adolescents Sponsors: University Hospital, Rouen Not yet recruiting
Psilocybin for Depression in Veterans
Conditions: Major Depression Interventions: Drug: Psilocybin; Drug: modafinil; Drug: zolpidem; Drug: pimavanserin Sponsors: VA Office of Research and Development Not yet recruiting
Phase 1: Thrive Together: A Feasibility and Acceptability Evaluation of Peer Mentoring for High Schoolers With ADHD and Their Caregivers
Conditions: Attention-Deficit/Hyperactivity Disorder (ADHD) Sponsors: Boston Children's Hospital; YMCA Not yet recruiting
Rehabilitation Through Virtual Immersion & Integrated Exposure for Mild Traumatic Brain Injury (ReVIVE for mTBI)
Conditions: Traumatic Brain Injuries; TBI (Traumatic Brain Injury); MTBI - Mild Traumatic Brain Injury; mTBI; Traumatic Brain Injury | Patient; Traumatic Brain Injury and Co-occurring Disorders; PTSD - Post Traumatic Stress Disorder Interventions: Device: Virtual Reality; Behavioral: Standard Psychotherapy Sponsors:…
TRIal of PPF3 vs. PlaCEbo in the TReatment of Children and AdolescenTs With NeurOdeveloPmental DisorderS
Conditions: Autism Disorder Interventions: Drug: PPF3; Drug: Placebo Sponsors: Holland Bloorview Kids Rehabilitation Hospital; Ontario Brain Institute (Funder); Purposeful Recruiting
Linear Accelerator Radiosurgical Anterior Capsulotomy With Task-based fMRI Identification of PERSonalized and PrEdictiVE Biomarkers of REsponse in Treatment-Refractory Obsessive-Compulsive Disorder (PERSEVERE Trial)
Conditions: Treatment-refractory Obsessive-compulsive Disorder (trOCD) Interventions: Device: Radiosurgical anterior capsulotomy Sponsors: University Hospitals Cleveland Medical Center Not yet recruiting
Microglial NUS1 deficiency drives dopaminergic neurodegeneration through intercellular iron dysregulation in Parkinson’s disease models
Nature Neuroscience, Published online: 26 October 2026; doi:10.1038/s41593-026-02499-3Using cellular and mouse models, this study reports that deficiency of the Parkinson’s disease risk gene NUS1 in microglia disrupts intercellular iron homeostasis, leading to neuronal iron overload and dopaminergic neurodegeneration.
Giving AI a seat at the peer review table
Nature Biotechnology, Published online: 26 October 2026; doi:10.1038/s41587-026-03369-wGiving AI a seat at the peer review table
Chronic progressive demyelination induces a microglial state with lysosomal dysfunction
Nature Neuroscience, Published online: 26 October 2026; doi:10.1038/s41593-026-02489-5Acute myelin injury responses are well defined, but microglia adaptations to chronic damage remain unclear. Mouse models reveal a chronic demyelination-associated microglial state marked by inflammation, lysosomal dysfunction and myelin-damaging activity.
A Sensorimotor-Interoceptive Model for Sensory Phenomena in Obsessive-Compulsive Disorder: Neural and Computational Mechanisms
Classical models of obsessive-compulsive disorder (OCD) grounded in cognitive-affective processes do not fully account for sensory phenomena (SP), including bodily discomfort, incompleteness, and not-just-right experiences that often precede or accompany compulsive behavior. To address this gap, we propose a sensorimotor-interoceptive…
Individualized brain mapping for neurosurgical planning
The need for personalised approaches in neurosurgery arises from marked variations in the distribution and performance of functional networks among individual brains. Functional MRI and diffusion tractography have been widely adopted for neurosurgical planning. However, the way in which neuroimaging…
Neoadjuvant durvalumab plus chemotherapy in resectable or borderline resectable non-small-cell lung cancer: the phase 2 MDT-BRIDGE trial
Nature Medicine, Published online: 26 October 2026; doi:10.1038/s41591-026-04742-7As presented at the ESMO Congress 2026: In the global phase 2 MDT-BRIDGE trial, neoadjuvant durvalumab plus chemotherapy in patients with resectable and borderline resectable non-small-cell lung cancer, followed by multidisciplinary reassessment, enabled…
Author Correction: Liquid biopsy for early detection of pancreatic ductal adenocarcinoma
Nature Medicine, Published online: 26 October 2026; doi:10.1038/s41591-026-04775-yAuthor Correction: Liquid biopsy for early detection of pancreatic ductal adenocarcinoma
News Feed
Is the oxytocin system a keystone in human wellbeing?
It has also taken over a century for science to fully realize that oxytocin is far more than a “female reproductive hormone.” Both the measurement and interpretation of the biochemical and functional properties of…
Asymmetric encoder-decoder U-net with hybrid attention and residual dilated convolution for brain tumor segmentation
InroductionThe accurate and automatic segmentation of brain tumors from magnetic resonance imaging is regarded as essential for clinical diagnosis and surgical planning. Nevertheless, the concurrent extraction of both local fine details and global contextual…
News
3048 results
STAT+: HHS relaxes security, transparency rules for health record software used by hospitals
The Trump administration removed several security, privacy and transparency requirements for vendors of EHR software.
Will the real Anthropic please stand up
This story originally appeared in The Algorithm, our weekly newsletter on AI. To get stories like this in your inbox first, sign up here. After weeks of frenzied speculation, Anthropic has filed its IPO prospectus. The 335-page document (100 pages or…
STAT+: House lawmaker probes PBMs for ‘punitive’ audits of independent pharmacies
A House lawmaker is investigating whether the three largest PMS targeted independent pharmacies withretaliatory audits.
STAT+: GSK sees its return to cancer start to pay off
A decade ago, GSK was out of oncology. It could soon pick up approval for its sixth cancer drug.
STAT+: Merck ADC drug cut risk of death by one-third in advanced endometrial cancer
A Phase 3 trial of a targeted drug developed by Merck and China’s Kelun-Biotech cut by one-third the risk of death in patients with advanced endometrial cancer.
The Download: everyday AI harms and the race to nuclear spaceflight
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Opinion: The focus on AI safety disasters ignores everyday harms —Sam Hiner, cofounder of the Young…
The focus on AI safety disasters ignores everyday harms
Consider what passes for success in technology policy. An AI company promises that its chatbot will not encourage suicide. A social media platform makes it more difficult for children to buy fentanyl. These are important protections, and they should have…
Assessment of the Seasonality of Depressive Symptoms in Adolescents
Conditions: Depressive Symptoms Interventions: Diagnostic Test: Measuring the intensity of the seasonality of depressive symptoms in adolescents Sponsors: University Hospital, Rouen Not yet recruiting
Psilocybin for Depression in Veterans
Conditions: Major Depression Interventions: Drug: Psilocybin; Drug: modafinil; Drug: zolpidem; Drug: pimavanserin Sponsors: VA Office of Research and Development Not yet recruiting
Phase 1: Thrive Together: A Feasibility and Acceptability Evaluation of Peer Mentoring for High Schoolers With ADHD and Their Caregivers
Conditions: Attention-Deficit/Hyperactivity Disorder (ADHD) Sponsors: Boston Children's Hospital; YMCA Not yet recruiting
Rehabilitation Through Virtual Immersion & Integrated Exposure for Mild Traumatic Brain Injury (ReVIVE for mTBI)
Conditions: Traumatic Brain Injuries; TBI (Traumatic Brain Injury); MTBI - Mild Traumatic Brain Injury; mTBI; Traumatic Brain Injury | Patient; Traumatic Brain Injury and Co-occurring Disorders; PTSD - Post Traumatic Stress Disorder Interventions: Device: Virtual Reality; Behavioral: Standard Psychotherapy Sponsors:…
TRIal of PPF3 vs. PlaCEbo in the TReatment of Children and AdolescenTs With NeurOdeveloPmental DisorderS
Conditions: Autism Disorder Interventions: Drug: PPF3; Drug: Placebo Sponsors: Holland Bloorview Kids Rehabilitation Hospital; Ontario Brain Institute (Funder); Purposeful Recruiting
Linear Accelerator Radiosurgical Anterior Capsulotomy With Task-based fMRI Identification of PERSonalized and PrEdictiVE Biomarkers of REsponse in Treatment-Refractory Obsessive-Compulsive Disorder (PERSEVERE Trial)
Conditions: Treatment-refractory Obsessive-compulsive Disorder (trOCD) Interventions: Device: Radiosurgical anterior capsulotomy Sponsors: University Hospitals Cleveland Medical Center Not yet recruiting
Microglial NUS1 deficiency drives dopaminergic neurodegeneration through intercellular iron dysregulation in Parkinson’s disease models
Nature Neuroscience, Published online: 26 October 2026; doi:10.1038/s41593-026-02499-3Using cellular and mouse models, this study reports that deficiency of the Parkinson’s disease risk gene NUS1 in microglia disrupts intercellular iron homeostasis, leading to neuronal iron overload and dopaminergic neurodegeneration.
Giving AI a seat at the peer review table
Nature Biotechnology, Published online: 26 October 2026; doi:10.1038/s41587-026-03369-wGiving AI a seat at the peer review table
Chronic progressive demyelination induces a microglial state with lysosomal dysfunction
Nature Neuroscience, Published online: 26 October 2026; doi:10.1038/s41593-026-02489-5Acute myelin injury responses are well defined, but microglia adaptations to chronic damage remain unclear. Mouse models reveal a chronic demyelination-associated microglial state marked by inflammation, lysosomal dysfunction and myelin-damaging activity.
A Sensorimotor-Interoceptive Model for Sensory Phenomena in Obsessive-Compulsive Disorder: Neural and Computational Mechanisms
Classical models of obsessive-compulsive disorder (OCD) grounded in cognitive-affective processes do not fully account for sensory phenomena (SP), including bodily discomfort, incompleteness, and not-just-right experiences that often precede or accompany compulsive behavior. To address this gap, we propose a sensorimotor-interoceptive…
Individualized brain mapping for neurosurgical planning
The need for personalised approaches in neurosurgery arises from marked variations in the distribution and performance of functional networks among individual brains. Functional MRI and diffusion tractography have been widely adopted for neurosurgical planning. However, the way in which neuroimaging…
Neoadjuvant durvalumab plus chemotherapy in resectable or borderline resectable non-small-cell lung cancer: the phase 2 MDT-BRIDGE trial
Nature Medicine, Published online: 26 October 2026; doi:10.1038/s41591-026-04742-7As presented at the ESMO Congress 2026: In the global phase 2 MDT-BRIDGE trial, neoadjuvant durvalumab plus chemotherapy in patients with resectable and borderline resectable non-small-cell lung cancer, followed by multidisciplinary reassessment, enabled…
Author Correction: Liquid biopsy for early detection of pancreatic ductal adenocarcinoma
Nature Medicine, Published online: 26 October 2026; doi:10.1038/s41591-026-04775-yAuthor Correction: Liquid biopsy for early detection of pancreatic ductal adenocarcinoma